ea0006dp29 | Diabetes, metabolism and cardiovascular | SFE2003
Milne H
, Burns C
, Minger S
, Persaud S
, Jones P
Embryonic stem cells (ES cells) represent a population of self renewing pluripotent cells, capable of differentiating into derivatives of the 3 embryonic germ layers and are therefore a promising source material for generation of replacement pancreatic beta cells for transplantation in type 1 diabetes. ES cells can be induced to undergo unregulated differentiation when cultured as floating clusters (embryoid bodies). Successful generation of pancreatic endocrine cells from ES ...